­­­­­­Myexa- 5000000 I.U 

Polymyxin B – 5000000 I.U Injection

Polymyxin B is a type of antibiotic medication that belongs to the class of polymyxin antibiotics. It is primarily used to treat bacterial infections caused by Gram-negative bacteria, particularly those that are resistant to other antibiotics.

Polymyxin B works by disrupting the integrity of the bacterial cell membrane, leading to cell death. It binds to the lipopolysaccharide component of the outer membrane of Gram-negative bacteria, causing the membrane to become permeable and resulting in leakage of cellular contents. This mode of action makes it effective against a wide range of Gram-negative bacteria, including some multidrug-resistant strains such as Pseudomonas aeruginosa.

Polymyxin B is typically administered intravenously or topically. Intravenous administration is reserved for severe systemic infections, while topical use is often employed for treating localized infections, particularly in the eyes or external ear canal.

As with any medication, there are potential side effects associated with the use of polymyxin B. Common side effects include irritation at the site of administration, such as redness, swelling, or pain. Systemic use of polymyxin B can lead to more severe side effects, such as kidney damage and neurotoxicity. Therefore, careful monitoring of kidney function and potential neurologic symptoms is important during treatment.