Buxetine-20

Duloxetine Hydrochloride 20mg. Tablets

INDICATIONS:

  • Depression
  • Anxiety Disorder
  • Also used for managing pain caused by fibromyalgia and diabetic peripheral neuropathy (DPNP)

DOSAGE:

  • The recommended dose: Initially: 20 mg/day, twice daily orally.
  • Maintenance dose:40 mg/daytwice daily
  • Maximum dose: 60 mg/day twice daily

ADMINISTRATION:

  • To be taken by mouth. It is usually taken once or twice a day with or without food

PRESENTATION:

  • Available as strip of 10 tablets.
Category:

Description

Buxetin (Duloxetine ) is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI) for oral administration. Its chemical name is (+)-(S)-N-methyl-y-(1-naphthyloxy)-2-thiophenepropylamine hydrochloride primarily targets major depressive disorder (MDD), generalized anxiety disorder (GAD), pain related to diabetic peripheral neuropathy and in some countries stress urinary incontinence (SUI) available as delayed release tablets.

MECHANISM OFACTION:

Duloxetine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and a less potent inhibitor of Hopamine reuptake. The antidepressant and pain inhibitory actions of duloxetine are believed to be related to its potentiation of serotonergic and noradrenergic activity in the CNS.

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