Mendytam-IV

Description

Mendytam-IV

Levetiracetam 100 mg /mg 5 ml Injection

Introduction

Levetiracetam Injection is an antiepileptic (anticonvulsant) medication used to treat seizures. It is available as a 100 mg/mL solution, typically provided in 5 mL vials. This form is used when oral administration is not possible, such as in emergency settings or during surgery.

Mode of Action

Levetiracetam works by:

Binding to synaptic vesicle protein 2A (SV2A) in the brain.
This modulates neurotransmitter release and reduces neuronal excitability.
It helps to stabilize nerve activity, thereby preventing seizures.

Unlike many other antiepileptic drugs, it does not affect GABA or glutamate receptors directly.

Indications:

Partial-onset seizures (≥1 month old)
Myoclonic seizures
Generalized tonic-clonic seizures
Status epilepticus (off-label)
Temporary oral replacement

Doses:
✅ Adults: 500–1500 mg IV every 12 hrs (infuse over 15 min)
✅ Children (4–15 yrs): 10–30 mg/kg every 12 hrs (Max 60 mg/kg/day)
✅ Infants (1 mo–<4 yrs): 7–21 mg/kg every 12 hrs

Precautions: