V3S – TZ 2.25 gm

Cefepime 2gm + Tazobactam 250 mg Injection

Cefepime and tazobactam are two separate medications that are often combined to treat various bacterial infections. Let’s look at each of them individually:

1. Cefepime: Cefepime is a broad-spectrum antibiotic belonging to the cephalosporin class. It is effective against a wide range of bacteria, including both gram-positive and gram-negative organisms. Cefepime works by inhibiting the synthesis of bacterial cell walls, leading to bacterial cell death. It is commonly used to treat infections such as pneumonia, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, and others.
2. Tazobactam: Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are enzymes produced by bacteria that can break down and inactivate certain antibiotics, such as penicillins and cephalosporins. Tazobactam inhibits these enzymes, thus restoring the activity of antibiotics against beta-lactamase-producing bacteria. It does not have significant antibacterial activity on its own but enhances the effectiveness of other antibiotics. Tazobactam is often combined with cefepime or other beta-lactam antibiotics to extend their spectrum of activity.

When cefepime and tazobactam are combined, the intention is to enhance the antibacterial effect of cefepime by preventing the degradation of the antibiotic by beta-lactamases produced by certain bacteria.